1 / SCD1 impairs the reparative properties of macrophages and microglia in the central nervous system.

Bogie JFJ, Elien Grajchen, Elien Wouters, Aida Garcia Corrales, Tess Dierckx, Sam Vanherle, Jo Mailleux, Pascal Gervois, Esther Wolfs, Jonas Dehairs, Jana Van Broeckhoven, Andrew Bowman, Ivo Lambrichts, Jan-Ake Gustafsson, Alan T. Remaley, Monique Mulder, Johannes V. Swinnen, Mansour Haidar, Shane R. Ellis, James M. Ntambi, Noam Zelcer, Jerome J.A. Hendriks. Journal of Experimental Medicine. 2020 May 4;217(5).

2 / Phloretin enhances remyelination by stimulating oligodendrocyte precursor cell differentiation.

Dierckx T, Vanherle S, Haidar M, Grajchen E, Mingneau F, Gervois P, Wolfs E, Bylemans D, Voet A, Nguyen T, Hamad I, Kleinewietfeld M, Bogie JFJ, Hendriks JJA. Proc Natl Acad Sci U S A. 2022 Nov 16;119(46):e2120393119. doi: 10.1073/pnas.2120393119. Epub 2022 Nov 7. PMID: 36343243; PMCID: PMC9674257.

3 / Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity.

​Grajchen E, Loix M, Baeten P, Côrte-Real BF, Hamad I, Vanherle S, Haidar M, Dehairs J, Broos JY, Ntambi JM, Zimmermann R, Breinbauer R, Stinissen P, Hellings N, Verberk SGS, Kooij G, Giera M, Swinnen JV, Broux B, Kleinewietfeld M, Hendriks JJA, Bogie JFJ. Cell Mol Immunol. 2023 Apr 12. doi: 10.1038/s41423-023-01011-2. Epub ahead of print. PMID: 37041314.

4 / Targeting lipophagy in macrophages improves repair in multiple sclerosis.

Mansour Haidar, Melanie Loix, Sam Vanherle, Tess Dierckx, Tim Vangansewinkel, Pascal Gervois, Esther Wolfs, Ivo Lambrichts, Jeroen F.J Bogie, Jerome J.A Hendriks. Autophagy. 2022 Mar 14;1-14.

5 / Phloretin suppresses neuroinflammation by autophagy-mediated Nrf2 activation in macrophages.

Dierckx T, Haidar M, Grajchen E, Wouters E, Vanherle S, Loix M, Boeykens A, Bylemans D, Hardonnière K, Kerdine-Römer S, Bogie JFJ, Hendriks JJA. J Neuroinflammation. 2021 Jul 4;18(1):148. doi: 10.1186/s12974-021-02194-z. PMID: 34218792; PMCID: PMC8254976.

6 / Perilipin-2 limits remyelination by preventing lipid droplet degradation.

Loix M, Wouters E, Vanherle S, Dehairs J, McManaman JL, Kemps H, Swinnen JV, Haidar M, Bogie JFJ, Hendriks JJA. Cell Mol Life Sci. 2022 Sep 13;79(10):515. doi: 10.1007/s00018-022-04547-0. PMID: 36100764.